The quote by Voltaire is an interesting one to remember by researchers. Once you decided to solve a research question and started literature review you need not abandon the problem totally at any time. The solution may take time and you may need to take breaks and divert your attention to some other activities, but if you are at it you are likely to solve it. Well sometimes you may not solve it, but if you still did some thinking and explored some ways to solve the problem and failed, you can leave your trail to somebody else. You may not be able to publish a paper on it. But you can still pass on your manuscripts. In this digital age, you can still self publish your research endeavour and leave the trail on online space.
Remember "No problem can withstand the assault of sustained thinking."
Add the quote of Einstein
"The significant problems we face cannot be solved at the same level of thinking we were at when we created them."